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Study Shows Proof Systemic Inflammatory Reaction to Silicone Breast Implants

Study Shows Proof Systemic Inflammatory Reaction to Silicone Breast Implants

PHILADELPHIA, MISSOURI, June 10, 2011 /NewsRelease/ - Females with silicone breast implants saw their particular c-reactive protein levels jump from an average 1.3 mg/L before surgery to 4.8 at 2 months after surgery and 4.3 at 6 months after surgery. By comparison, women receiving liposuction saw a decline in c-reactive protein levels by 6 months from an average of 3.5 before surgery, which remained constant at two months post-surgery, but dropped to 2.2 at 6 months after surgery.

When the FDA lifted its 10 year moratorium on the use of silicone breast implants for cosmetic breast augmentation in November 2006, it stated that the preponderance of evidence suggested there was no relationship between silicone breast implants and breast cancer as well as autoimmune disorders, charges that had led to the moratorium. However, it also suggested that breast implant manufacturers as well as surgeons should always study silicone breast implants for the next decade to build up evidence with regards to those risks.

Currently, five years later, one study implies a mechanism for the possible connection between silicone breast implants and systemic issues. The study, published in the March issue regarding Aesthetic Plastic Surgery, compared the immune reply of breast augmentation people with those of lipo patients to determine whether the two groups of sufferers experienced different immune responses. The study showed that a protein connected with inflammatory reactions increased significantly in women receiving breast augmentations, but not in those receiving liposuction.

According to Philadelphia chicago plastic surgeon Dr. David Bottger, he author suggest that this finding could signal ongoing immunogenicity of silicone. While that is certainly possible, c-reactive proteins are known to talk with a number of processes within the body, so it’s hard to declare what this indicates about silicone breast implants. What we can say for sure is that nothing in your 50-year experience with silicone breast implants actually signifies there is a causal relationship between them and autoimmune disorders or breast cancer.

Women who are considering silicone breast implants or even who already have silicone breast implants are encouraged to talk to their doctor about the science behind the safety of silicone breast implants.

Concerning Dr.

Breast Augmentation and Liposuction Blog

The FDA has released a safety update on silicone gel breast implants , the first since the lifting of the moratorium in November 2006. The update is derived from results from the 10-year study of Allergan's silicone gel breast implants and 8-year study of Mentor's silicone gel breast implants, enrolling a total of nearly 2000 patients. The report looks at silicone gel breast implants as medical devices, not at breast augmentation as a cosmetic surgery, so it looks at only part of the story for women considering breast augmentation. However, this aspect of breast implants is extremely important, and we will take several months to consider a number of elements in the report to help women understand the potential risks and complications of breast augmentations.

To me, the most crucial statement by the FDA is "The benefits and risks of breast implants are sufficiently well understood for women to make informed decisions about their use." After decades of uncertainty about possible diseases or conditions related to breast implants, the FDA now feels we know enough about them to make definitive recommendations, and eliminate lingering doubts about autoimmune and connective tissue disorders.

Here is a summary of the report's other key findings:

"Silicone gel breast implants have a reasonable assurance of safety and effectiveness," "Despite frequent local complications and adverse outcomes." Risks of complications and adverse outcomes increase with time: "Women with breast implants will need to monitor their breasts for local complications for the rest of their lives." The most frequent complications and adverse outcomes are: Capsular contracture Reoperation Implant removal Breast implants may increase the risk of anaplastic large cell lymphoma (not breast cancer), which nonetheless remains very small Up to 20% of breast augmentation patients are expected to need a second surgery within the first 8 to 10 years, but routine replacement is not necessary There is no association between silicone gel breast implants and connective tissue disease, breast cancer, or reproductive problems, but it remains possible that very rare or very slow-developing conditions may not be detectable in the current data MRI remains the only effective method for detecting silent rupture of silicone gel breast implants

The FDA also notes that very low follow-up rates (66% for the Allergan study and 58% for the Mentor study) may limit our ability to interpret the data.

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